Association between NLPR1, NLPR3, and P2X7R Gene Polymorphisms with Partial Seizures
Table 4
Genotypic and allelic distribution of the NLRP1 gene between female patients and controls .
SNP
Genotype/allele
Case (%)
Control (%)
value
OR (95% CI)
value
rs8079034
CC
57 (77.0)
75 (73.5)
0.513 (1.336)
1.00
Referent
CT
14 (18.9)
25 (24.5)
1.357 (0.648–2.843)
0.418
TT
3 (4.1)
2 (2.0)
0.507 (0.082–3.133)
0.465
CT + TT
17 (23.0)
27 (26.5)
0.597 (0.280)
1.207 (0.601–2.425)
0.597
C
128 (86.5)
175 (86.8)
0.851 (0.035)
1.00
Referent
T
20 (13.5)
29 (14.2)
1.061 (0.574–1.959)
0.851
rs878329
GG
54 (73.0)
64 (62.7)
0.350 (2.009)
1.00
Referent
GC
18 (24.3)
35 (34.3)
4.641 (0.836–3.219)
0.150
CC
2 (2.7)
3 (3.0)
1.266 (0.204–7.854)
0.800
GC + CC
20 (27.0)
38 (37.3)
0.154 (2.031)
1.603 (0.836–3.075)
1.603
G
126 (85.1)
163 (79.9)
0.206 (1.599)
1.00
Referent
C
22 (14.9)
41 (20.1)
1.441 (0.817–2.542)
0.208
CI, confidence interval; OR, odds ratio. value for genotype and allele frequencies in cases and controls using 2-sided test. values adjusted by age and gender using logistic regression.
