BioMed Research International / 2018 / Article / Tab 1 / Review Article
Donation after Circulatory Death in Paediatric Liver Transplantation: Current Status and Future Perspectives in the Machine Perfusion Era Table 1 Donation after circulatory death in paediatric liver transplantation.
Author Number of recipients Recipient age Recipient gender (M/F) Type of graft Donor age (years) Donor cause of death ITU donor stay (days) Donor WIT (minutes) CIT (hours) UK DCD Risk- Follow-up Patient status Complications Muiesan et al. 2006 [17 ] Bartlett et al. 2010 [18 ] 14 7 yr (8 mo–16 yr) 7 M/0 F 4: whole graft 8: reduced graft 1: split LLS 1: auxiliary LT 23 (10–64) -7 Anoxia -4 Trauma -3 CVA 5 (2–4) 16 (11–29) 7 (5.5–8.4) 2 41.8 (1.7–74) months All alive 2: pleural effusion 1: sepsis 4: early ACR 2: ductopenic rejection Abt et al. 2006 [19 ] 19 yr12 M/7 F Whole liver 12.2 ± 14.4 -10 Trauma -7 Anoxia -1 CVA -1 Others NA 2 60 months NA 2: (10.5%) retransplantation 1: (5.3%) PNF Perera et al. 2009 [20 ] 2 6 weeks; 7 yr 0 M/2 F Reduced graft 14; 20 -1 Trauma -1 Meningitis NA 22; 25 8 h 29 min; 9 h 34 min 5 6 months; 3 years All alive 1: early ACR 1: ischemic cholangiopathy Gozzini et al. 2010 [21 ] 4 9.5 (0.2–17) yr 1 M/3 F 2: reduced graft 2: whole graft 14.2 (11–20) -2 Trauma -1 Anoxia -1 Meningitis 2.5 (1–5) 12 (10–15) 7 (6–8) 2 19 (8.1–43.4) months All alive 2: early ACR 2: ischemic cholangiopathy Gelas et al. 2012 [22 ] 1 2 weeks 1 M/0 F ABO-incompatible reduced graft NA Anoxia 4 15 6 2 13 months All Alive Early ACR; chronic rejection Hong et al. 2014 [23 ] 7 28.4 (9.6–59.2) mo 3 M/4 F Whole graft 2.4 (0.3–6) NA <5 24 5 (4–7) 3 10 years All Alive 1: anastomotic biliary stricture van Rijn et al. 2017 [24 ] 3 8.6 (6–13) yr NA Whole liver 5 (3–9) NA NA 25 (20–31) 8 (7–9) 5 10 years 1 Dead 2 Alive 2: hepatic artery thrombosis 1: portal vein thrombosis
ACR, acute cellular rejection; F, female; LLS, left lateral segment; LT, liver transplantation; M, male; mo, months; NA, not available; PNF, primary nonfunction; yr, years .
-DCD Risk Score was calculated without body mass index and Paediatric End-Stage Liver Disease score values due to lack of data available.