Resveratrol Prevents Diabetic Cardiomyopathy by Increasing Nrf2 Expression and Transcriptional Activity

Table 4

Effects of resveratrol on cardiac dysfunction and heart rate in anesthetized DM mice (6 months).

Group	HR (beats/min)	LVID (mm)	IVS (mm)	LVPW (mm)	% EF (%)	% FS (%)
Control	483 ± 27	3.6 ± 0.19	0.76 ± 0.04	0.85 ± 0.09	89.35 ± 3.70	60.10 ± 4.86
Resveratrol	478 ± 21	3.58 ± 0.12	0.78 ± 0.02	0.92 ± 0.03	88.24 ± 4.52	56.25 ± 4.73
DM	464 ± 23	3.99 ± 0.12	0.99 ± 0.02	1.05 ± 0.02	66.25 ± 3.25	36.00 ± 3.63
DM/resveratrol	468 ± 17	3.76 ± 0.14^#	0.83 ± 0.02^#	0.90 ± 0.02^#	80.05 ± 3.60^#	48.22 ± 4.50^#

Data are presented as means ± SEM. LVID = LV end-diastolic diameter; LVPW = LV posterior wall; IVS = interventricular septum; FS = fractional shortening; EF = ejection fraction. versus control. versus DM group.