Research Article

No Association of CALCA Polymorphisms and Aseptic Loosening after Primary Total Hip Arthroplasty

Table 2

Clinical characteristics and CALCA P1 genotype distribution in patients with aseptic loosening.

AllCALCA P1 genotypep-value
CCCTTT

Aseptic loosening
n (%)320 (100)34 (10.5)139 (43.0)147 (45.5)
Age at implantation (y)55.0 ± 13.3755.67 ± 14.754.63 ± 12.355.24 ± 14.070.891
Age at replantation (y)66.59 ± 12.0367.12 ± 11.766.29 ± 11.766.76 ± 12.470.912
Gender
 Female (%)225 (70.3)25 (11.1)99 (44)101 (44.9)0.817
 Male (%)95 (29.7)9 (9.5)40 (42.1)46 (48.6)
BMI (kg/m2)26.86 ± 5.026.69 ± 5.026.28 ± 4.8627.37 ± 5.30.648
First cup with cement 
(n=294)
 no107 (36.4)8 (25)49 (39.2)50 (36.5)0.329
 yes187 (63.6)24 (75)76 (60.8)87 (63.5)
First stem with cement 
(n= 292)
 no105 (36)10 (9.5)42 (40)53 (50.5)0.743
 yes187 (64)21(11.2)80 (42.9)86 (45.9)

Data are numbers with percentages given in brackets and numbers with standard deviation, respectively. Categorical variables were analysed by statistics. P values were calculated using ANOVA for continuous variables.