No Association of CALCA Polymorphisms and Aseptic Loosening after Primary Total Hip Arthroplasty
Table 6
Median time to aseptic loosening according to gender and CALCA genotype.
n (%)
All 315
CALCA P1- genotype
p-value
CC 34 (10.8)
CT 136 (43.2)
TT 145 (46.0)
MTAL, mo (range)
128 (1-431)
139 (1-357)
128 (1-424)
120 (1-431)
0.971
All
CALCA P2- genotype
p-value 0.77
II
ID
DD
n (%)
159
144 (90.6)
14 (8.8)
1 (0.6)
MTAL, mo (range)
92 (1-384)
90 (1-384)
104 (15-254)
73 (73-73)
All
CALCA P3- genotype
TT
TC
p-value
n (%)
159 (100)
155 (97.5)
4 (2.5)
MTAL, mo (range)
92 (1-384)
92 (1-384)
138 (50-254)
0.339
All
CALCA P4- genotype
p-value 0.976
AA
AT
TT
n (%)
158
76 (48.1)
63 (39.9)
19 (12.0)
MTAL, mo (range)
92 (1-384)
88 (1-344)
92 (1-369)
101 (1-357)
MTAL, median time to aseptic loosening. Data are numbers with percentages given in brackets and medians with ranges given in brackets, respectively. P values were calculated using Kruskal-Wallis test for nonparametric variables. Jonckheere-Terpstra test for linear comparison of nonparametric variables, p=0.160.
