Research Article

Propofol Reversed Hypoxia-Induced Docetaxel Resistance in Prostate Cancer Cells by Preventing Epithelial–Mesenchymal Transition by Inhibiting Hypoxia-Inducible Factor 1α

Table 6

The cell viability of PC cells treated with docetaxel alone under normoxia or hypoxia conditions or docetaxel plus propofol under hypoxia conditions.

Cell lines (μM)
NormoxicHypoxicHypoxic + propofol

PC355.73 (46.25 to 65.21)64.58 (54.11 to 75.05)65.54 (52.64 to 78.43)
DU14531.44 (29.31 to 33.58)32.20 (27.81 to 36.59)31.63 (28.10 to 35.17)
22RV126.61 (23.49 to 29.73)31.65 (27.96 to 35.35)31.10 (27.38 to 34.81)

values show docetaxel concentration [μM, mean (95% confidence intervals)].