In Vitro Susceptibility of Mycobacterium abscessus and Mycobacterium fortuitum Isolates to 30 Antibiotics

Table 3

The comparison of drug resistance rate of M. abscessus isolates from various studies.

district/nation	year	Test method	Tetracyclines		Glycylcycline	Carbapenems					Aminoglycosides			Fluoroquinolones			Macrolides			source
			DOX	MNO	TGC	IMP	MEM	LNZ	SXT/SOX^3	FOX	AMK	TOB	STR	CIP	MXF	LVX	CLR-ERT	CLR-LRT	AZM
Shanghai	2017	1	14 (70%)	11 (55%)	8 (40%)	13 (65%)	-	3 (15%)	18 (90%)	2 (10%)	2 (10%)	12 (60%)	20 (100%)	19 (95%)	19 (95%)	19 (95%)	-	9 (45%)	2 (10%)	This study
Taiwan	2017	1	66 (99%)	66 (99%)	-	41 (61%)	-	47 (70%)	60 (90%)	14 (21%)	4 (6%)	-	-	60 (90%)	63 (94%)	-	5 (7%)	19 (28%)	-	[21]
Korea	2017	1	-	-	-	17 (18%)	-	5 (5%)	-	10 (10%)	6 (6%)	-	-	94 (99%)	88 (93%)	-	9 (9%)	39 (41%)	-	[22]
Beijing	2016	1	-	-	4 (18%)	9 (41%)	-	2 (9%)	10 (45%)	7 (32%)	1 (5%)	8 (36%)	-	-	6 (27%)	17 (77%)	3 (14%)	-	17 (77%)	[23]
Shanghai	2016	1	52 (98%)	-	-	52 (98%)	-	11 (21%)	-	15 (28%)	1 (2%)	44 (83%)	-	-	51 (96%)	-	15 (28%)	36 (68%)	-	[24]
UK	2015	2	-	-	3 (1%)	-	534 (99%)	311 (96%)	-	531 (96%)	74 (14%)	-	-	495 (99%)	257 (98%)	-	33 (6%)	-	191 (38%)	[25]
Fujian et al.	2015	1	36 (65%)	31 (56%)	2 (4%)	-	16 (29%)	2 (4%)	-	17 (31%)	0 (0%)	30 (55%)	52 (95%)	31 (56%)	12 (22%)	29 (53%)	18 (33%)	-	12 (22%)	[26]
Singapore	2015	1	235 (80%)	-	-	50 (20%)	-	50 (16%)	95 (94%)	8 (3%)	1 (0.9%)	282 (98%)	-	293 (94%)	115 (93%)	-	11 (3%)	-	-	[27]
Australia	2015	1	32 (84%)	-	-	26 (68%)	-	7 (18%)	35 (92%)	7 (18%)	2 (5%)	22 (58%)	-	36 (95%)	35 (92%)	-	-	18 (47%)	-	[28]
Beijing	2014	1	-	-	-	7 (10%)	-	2 (3%)	-	1 (1%)	1 (1%)	-	-	-	10 (14%)	68 (97%)	22 (31%)	38 (54%)	3 (4%)	[4]
Korea	2014	1	-	-	-	-	-	-	-	-	40 (10%)	-	-	361 (89%)	319 (79%)	-	64 (16%)	186 (46%)	-	[29]
Japan	2013	1	139 (97%)	119 (83%)	73 (51%)	34 (24%)	-	16 (11%)	143(100%)	-	7 (5%)	44 (31%)	87 (61%)	137 (96%)	135 (94%)	-	18 (13%)	-	-	[30]
Guangdong	2013	1	-	-	-	15 (21%)	-	-	-	3 (4%)	0 (0%)	-	-	56 (80%)	-	-	10 (14%)	-	-	[31]
Korea	2008	1	60 (81%)	-	-	8 (11%)	-	-	-	0 (0%)	0 (0%)	22 (30%)	-	13 (18%)	5 (7%)	-	2 (3%)	-	-	[32]
Taiwan	2003	1	85 (92%)	-	-	17 (10%)	91 (99%)	39 (42%)	91 (99%)	4 (4%)	4 (4%)	28 (32%)	-	87 (96%)	75 (82%)	88 (96%)	10 (11%)	-	44 (48%)	[33]

1 means broth microdilution method and 2 means disc diffusion method.
“-“ means the results are not available.
SXT=trimethoprim-sulfamethoxazole. SXT and SOX have the same mainly effective ingredient sulfamethoxazole, so we compare the results together.