The Polymorphism in ADORA3 Decreases Transcriptional Activity and Influences the Chronic Heart Failure Risk in the Chinese

Figure 2

Effects of the promoter polymorphisms on the transcription activity of human ADORA3 promoter. (a) Schematic representation of reporter gene constructs that contained the ADORA3 promoter region with the rs1544223. (b) Relative luciferase activity of report gene containing different allele. Relative luciferase activity is represented as the ratio of firefly luciferase activity to renilla luciferase. Values represent mean ± SD. Every test was repeated three times. Statistical differences were evaluated with Student’s -test.

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