Research Article
SRMDAP: SimRank and Density-Based Clustering Recommender Model for miRNA-Disease Association Prediction
Table 2
Prediction result of SRMDAP and other methods for LOOCV.
| Disease names | Number of related_miRNAs | AUC | SRMDAP | RLSMDA | KATZ | Liu’s method |
| Carcinoma, hepatocellular | 208 | 0.7639 | 0.6909 | 0.6881 | 0.4807 | Breast neoplasms | 197 | 0.7776 | 0.6814 | 0.6779 | 0.4147 | Stomach neoplasms | 174 | 0.7591 | 0.6635 | 0.6791 | 0.5498 | Colorectal neoplasms | 143 | 0.7929 | 0.6647 | 0.6895 | 0.4699 | Melanoma | 136 | 0.7958 | 0.6584 | 0.6673 | 0.4804 | Lung neoplasms | 128 | 0.8874 | 0.7198 | 0.7675 | 0.5243 | Heart failure | 120 | 0.7538 | 0.6608 | 0.6622 | 0.5040 | Prostatic neoplasms | 116 | 0.8076 | 0.6704 | 0.7054 | 0.5440 | Ovarian neoplasms | 112 | 0.8732 | 0.7194 | 0.7705 | 0.5382 | Carcinoma, renal cell | 104 | 0.7367 | 0.5815 | 0.6126 | 0.4932 | Pancreatic neoplasms | 97 | 0.8687 | 0.6829 | 0.7288 | 0.5355 | Carcinoma, non-small-cell lung | 94 | 0.8322 | 0.6873 | 0.6981 | 0.5470 | Glioblastoma | 94 | 0.7686 | 0.6421 | 0.6522 | 0.5644 | Urinary bladder neoplasms | 90 | 0.7935 | 0.6231 | 0.6635 | 0.5475 | Carcinoma, squamous cell | 78 | 0.8637 | 0.7179 | 0.7200 | 0.5398 | Colonic neoplasms | 77 | 0.8271 | 0.6582 | 0.6859 | 0.5490 | Glioma | 71 | 0.8212 | 0.6727 | 0.7146 | 0.5591 | Esophageal neoplasms | 70 | 0.7789 | 0.6126 | 0.6383 | 0.4781 |
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