Evaluation of Erythroid Disturbance and Thiol-Disulphide Homeostasis in Patients with Psoriasis

Table 2

Hematologic, inflammatory, and disulphide-homeostasis studies of the healthy controls and psoriasis patients.

		Healthy controls; ()	Psoriasis patients; ()	-value
Hemoglobin (g/dL)	Median; IQR	13.5; 1.1	13.2; 1.6	0.160
	(min, max)	(12.1, 15.6)	(12.0, 15.9)
Mean corpuscular volume (fL)	Mean ± SD	84.76 ± 3.87	88.45 ± 3.45	0.001
	(min, max)	(79, 93)	(80, 95)
Red cell distribution width (%)	Median; IQR	12.8; 0.8	13.2; 1.1	0.001
	(min, max)	(11.8, 14.6)	(12.0, 16.1)
Leukocyte count (×10^9/L)	Mean ± SD	7.4 ± 1.3	7.3 ± 2.0	0.791
	(min, max)	(3.9, 9.8)	(1.2, 12.0)
C-reactive protein (mg/dl)	Median; IQR	3.5; 1.7	9.0; 6.5	0.001
	(min, max)	(2.2, 18.9)	(2.5, 22.0)
Native thiol (µmol/L)	Median; IQR	423.05; 89.5	384.36; 118.1	0.009
	(min, max)	(129.7, 491.9)	(174.7, 550.9)
Total thiol (µmol/L)	Median; IQR	456.05; 84.2	425.17; 115.1	0.074
	(min, max)	(139.8, 533.2)	(228.1, 610.5)
Disulphide (µmol/L)	Median; IQR	15.03; 8.80	18.75; 6.79	0.001
	(min, max)	(1.9, 36.0)	(6.5, 36.0)
Disulphide/native thiol (%)	Median; IQR	3.59; 1.90	5.09; 1.90	0.001
	(min, max)	(0.6, 12.5)	(2.3, 15.3)
Disulphide/total thiol (%)	Median; IQR	3.35; 1.64	4.62; 1.56	0.001
	(min, max)	(0.6, 10.0)	(2.2, 11.7)
Native thiol/total thiol (%)	Median; IQR	93.29; 3.28	90.76; 3.12	0.001
	(min, max)	(80.0, 98.7)	(76.6, 95.6)

IQR: interquartile range, SD: standard deviation; was accepted to be statistically significant.