Lipidomic Profile Revealed the Association of Plasma Lysophosphatidylcholines with Adolescent Obesity

Table 1

Demographic and clinical characteristics^a of the male adolescents.

	Normal-weight group (n = 50)	Obese group (n = 50)	NN group (n = 25)	NA group (n = 25)	ON group (n = 25)	OA group (n = 25)
Age (years)	14.68 ± 0.47	14.72 ± 0.61	14.68 ± 0.48	14.68 ± 0.48	14.72 ± 0.61	14.72 ± 0.61
Weight (kg)	59.31 ± 6.27	93.38 ± 12.53	58.39 ± 4.96	60.22 ± 7.35	87.71 ± 10.1	99.0 ± 12.31^&
BMI (kg/m^2)	19.85 ± 1.63	30.80 ± 3.93	19.56 ± 1.21	20.13 ± 1.94	29.50 ± 3.91	32.10 ± 3.56^&
TG (mmol/L)	0.93 ± 0.50	1.27 ± 0.84	0.57 ± 0.20	1.29 ± 0.46^##	0.62 ± 0.23	1.92 ± 0.71^&&
TC (mmol/L)	3.77 ± 0.79	4.31 ± 1.32	3.22 ± 0.29	4.33 ± 0.73^##	3.14 ± 0.42	5.48 ± 0.73^&&
LDL-C (mmol/L)	3.13 ± 1.03	3.91 ± 1.75	2.30 ± 0.28	3.96 ± 0.81^##	2.33 ± 0.53	5.50 ± 0.88^&&
HDL-C (mmol/L)	1.40 ± 0.29	1.25 ± 0.27	1.56 ± 0.25	1.25 ± 0.23^##	1.42 ± 0.21	1.09 ± 0.22^&&

^aAll values are presented as the means ± SD. TG, triglyceride; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; NN, normal weight with traditional normal clinical plasma lipid levels; NA, normal weight with traditional abnormal clinical plasma lipid levels; ON, obese with traditional normal clinical plasma lipid levels; OA, obese with traditional abnormal clinical plasma lipid levels; BMI, body mass index. Traditional abnormal clinical plasma lipid levels were defined as abnormal levels of at least 2 of the 4 lipids: TG ≥ 1.1 mmol/L; TC ≥ 4.403 mmol/L; LDL-C ≥ 2.85 mmol/L; and HDL-C ≤ 1.17 mmol/L. Obese group vs. normal-weight group ; obese group vs. normal-weight group ; ^##NA vs. NN ; ^&&OA vs. ON ; ^&OA vs. ON .