Lipidomic Profile Revealed the Association of Plasma Lysophosphatidylcholines with Adolescent Obesity

Table 3

Potential biomarkers of adolescent obesity identified in the lipidomic analysis of normal-weight groups and obese groups with different clinical plasma lipid levels ().

	O (50) vs. N (50)		ON (n = 25) vs. NN (n = 25)		OA (n = 25) vs. NA (n = 25)
	VIP	value	VIP	value	VIP	value
LPC18:2	2.21	6.74 ×	2.21	1.08 ×	1.44	2.00 ×
LPC18:1	2.33	4.04 ×	2.22	9.91 ×	1.59	2.00 ×
LPC20:2	1.91	1.92 ×	1.80	4.40 ×	1.18	3.00 ×
LPC20:1	2.01	2.33 ×	1.62	6.67 ×	1.50	4.00 ×
LPC20:0	1.94	3.61 ×	1.79	7.33 ×	1.32	2.00 ×

and . NN, normal weight with traditional normal clinical plasma lipid levels; NA, normal weight with traditional abnormal clinical plasma lipid levels; ON, obese with traditional normal clinical plasma lipid levels; OA, obese with traditional abnormal clinical plasma lipid levels; LPC x: y, lysophosphatidylcholines with acyl chain length x and y double bonds.