MiR-195-5p Promotes Cardiomyocyte Hypertrophy by Targeting MFN2 and FBXW7

Figure 2

The miR-195-3p/-5p effect on hypertrophy induced by AngII in H9c2 cells. (a, b) In AngII-stimulated H9c2 cardiomyocytes after both miR-195-5p mimics and inhibitors transfecting, the ANP and BNP mRNA expression levels were measured using qRT-PCR. (c) Changes of cell surface area in AngII-treated cells with or without the inhibitor of miR-195-5p. (d, e) Effect of miR-195-3p mimic/inhibitor on expression status of ANP and BNP in induced-hypertrophic cardiomyocytes. The presentation of data is as the mean ± SD; , p < 0.05, and n = 3.