Research Article

Vasculogenic Mimicry Formation Is Associated with Erythropoietin Expression but Not with Erythropoietin Receptor Expression in Cervical Squamous Cell Carcinoma

Table 1

IHC expression of EPO/EPO-R and VM formation in normal cervix, LSIL, HSIL and CSCC, respectively.

GroupnEPOEPO-RVM
- (%)+ (%)P- (%)+ (%)P- (%)+ (%)P

Normal cervix2018(90.00)2(10.00)1.55817(85.00)3(15.00)1.29020(100.00)0(0.00)
LSIL2015(75.00)5(25.00)3.37514(70.00)6(30.00)4.01820(100.00)0(0.00)
HSIL2512(48.00)13(52.00)5.32710(40.00)15(60.00)5.60720(100.00)0(0.00)9.886
CSCC7618(23.68)58(76.32)29.709≤0.0013(17.11)63(82.89)33.972≤0.0049(64.47)27(35.53)9.886

a. normal cervix versus LSIL; b. LSIL versus HSIL; c. HSIL versus CSCC; d. CSCC versus normal cervix.
P<0.05, statistically significant