Vasculogenic Mimicry Formation Is Associated with Erythropoietin Expression but Not with Erythropoietin Receptor Expression in Cervical Squamous Cell Carcinoma

Table 2

Associations of EPO/EPO-R expression and VM formation with clinicopathological parameters of CSCC.

Parameter	n	EPO				EPO-R				VM
		- (%)	+ (%)		P	- (%)	+ (%)		P	- (%)	+ (%)		P
Age(years)
⩽40	30	5(16.67)	25(83.33)	1.350	0.245	4(13.33)	26(86.67)	0.497	0.481	19(63.33)	11(36.67)	0.028	0.867
40	46	13(28.26)	33(71.74)			9(19.57)	37(80.43)			30(65.22)	16(34.78)
Tumor size(cm)
⩽4	48	11(22.92)	37(77.08)	0.042	0.837	8(16.67)	40(83.33)	0.018	0.894	33(68.75)	15(31.25)	1.040	0.308
4	28	7(25.00)	21(75.00)			5(17.86)	23(82.14)			16(57.14)	12(42.86)
FIGO stage
	42	11(26.19)	31(73.81)	0.326	0.568	8(19.05)	34(80.95)	0.250	0.617	33(78.57)	9(21.43)	8.146	0.004
	34	7(20.59)	27(79.41)			5(14.71)	29(85.29)			16(47.06)	18(52.94)
Histological types
Keratinizing	25	8(32.00)	17(68.00)	1.425	0.233	7(38.00)	18(72.00)	3.119	0.077	19(76.00)	6(24.00)	2.161	0.142
Non-keratinizing	51	10(19.61)	41(80.39)			6(11.76)	45(88.24)			30(58.82)	21(41.18)
Lymphovascular space involvement
Positive	33	5(15.15)	28(84.85)	2.349	0.125	3(9.09)	30(90.91)	2.642	0.104	14(42.42)	19(57.58)	12.380	0.001
Negative	43	13(30.23)	30(69.77)			10(23.26)	33(76.74)			35(76.74)	8(23.26)
Lymph node metastasis
Positive	31	5(16.13)	26(83.87)	1.653	0.198	4(12.90)	27(87.10)	0.652	0.419	13(41.94)	18(58.06)	11.611	0.001
Negative	45	13(28.89)	32(71.11)			9(20.00)	36(80.00)			36(80.00)	9(20.00)

P<0.05, statistically significant.