BioMed Research International / 2019 / Article / Tab 2 / Research Article
Vasculogenic Mimicry Formation Is Associated with Erythropoietin Expression but Not with Erythropoietin Receptor Expression in Cervical Squamous Cell Carcinoma Table 2 Associations of EPO/EPO-R expression and VM formation with clinicopathological parameters of CSCC.
Parameter n EPO EPO-R VM - (%) + (%) P - (%) + (%) P - (%) + (%) P Age(years) ⩽40 30 5(16.67) 25(83.33) 1.350 0.245 4(13.33) 26(86.67) 0.497 0.481 19(63.33) 11(36.67) 0.028 0.867 40 46 13(28.26) 33(71.74) 9(19.57) 37(80.43) 30(65.22) 16(34.78) Tumor size(cm) ⩽4 48 11(22.92) 37(77.08) 0.042 0.837 8(16.67) 40(83.33) 0.018 0.894 33(68.75) 15(31.25) 1.040 0.308 4 28 7(25.00) 21(75.00) 5(17.86) 23(82.14) 16(57.14) 12(42.86) FIGO stage 42 11(26.19) 31(73.81) 0.326 0.568 8(19.05) 34(80.95) 0.250 0.617 33(78.57) 9(21.43) 8.146 0.004 34 7(20.59) 27(79.41) 5(14.71) 29(85.29) 16(47.06) 18(52.94) Histological types Keratinizing 25 8(32.00) 17(68.00) 1.425 0.233 7(38.00) 18(72.00) 3.119 0.077 19(76.00) 6(24.00) 2.161 0.142 Non-keratinizing 51 10(19.61) 41(80.39) 6(11.76) 45(88.24) 30(58.82) 21(41.18) Lymphovascular space involvement Positive 33 5(15.15) 28(84.85) 2.349 0.125 3(9.09) 30(90.91) 2.642 0.104 14(42.42) 19(57.58) 12.380 0.001 Negative 43 13(30.23) 30(69.77) 10(23.26) 33(76.74) 35(76.74) 8(23.26) Lymph node metastasis Positive 31 5(16.13) 26(83.87) 1.653 0.198 4(12.90) 27(87.10) 0.652 0.419 13(41.94) 18(58.06) 11.611 0.001 Negative 45 13(28.89) 32(71.11) 9(20.00) 36(80.00) 36(80.00) 9(20.00)
P<0.05, statistically significant.