Role of MMP-2(-1306 C/T) and TIMP-2(-418G/C) Polymorphism in Chinese Han Patients with Acne Vulgaris

Figure 2

Gene-gene interaction of MMP-2 and TIMP-2 in acne patients and healthy controls. The combined effects of MMP-2 (-1306) C>T and TIMP-2 (-418) G>C polymorphisms were analyzed by gene interaction analysis. CT-GG and CT-GC genotype in patients with acne vulgaris were significantly higher than those in normal controls (p<0.001, OR=0.258; p <0.05, OR=0.332). MMP-2 and TIMP-2 gene polymorphism in acne.