Role of MMP-2(-1306 C/T) and TIMP-2(-418G/C) Polymorphism in Chinese Han Patients with Acne Vulgaris

Table 4

Correlation between family history and severity of acne vulgaris.

	Family history
	Yes (%)	No (%)	OR (95%CI)	P
Group
Controls	41 (33.9)	80 (66.1)	Reference
Patients	141 (56.2)	110 (43.8)	2.036 (1.032-4.016)	<0.001
Patients Gender
Male	47 (33.3)	47 (42.7)	Reference
Female	94 (66.7)	63 (57.3)	0.670 (0.400-1.122)	0.127
Age of onset	18.60±5.30	19.54±6.04		0.194
Severity
Mild	13 (9.2)	30 (27.3)	Reference
Moderate	69 (48.9)	48 (43.6)
Severe	59 (41.8)	32 (29.1)		<0.001
Moderate+Severe	128 (90.8)	80 (72.7)	3.692 (1.819-7.497)	<0.001

OR: odds ratio. CI: confidence interval.