Research Article
Postoperative Monocyte Count Change Is a Better Predictor of Survival Than Preoperative Monocyte Count in Esophageal Squamous Cell Carcinoma
Table 1
Demographic and clinical data of 686 ESCC patients accroding to AMC change.
| | Charateristics | Total (N=686), % | AMCc | P value | | Increased (N=573), % | Decreased (N=113), % |
| | Sex | Male | 583 (85.0) | 480 (83.8) | 103 (91.2) | 0.045 | | | Female | 103 (15.0) | 93 (16.2) | 10 (8.8) | | Age (years) | ⩽60 | 316 (46.1) | 270 (47.1) | 46 (40.7) | 0.211 | | | >60 | 370 (53.9) | 303 (52.9) | 67 (59.3) | | Pathology grade | Well differentiated | 49 (7.1) | 44 (7.7) | 5 (4.4) | 0.335 | | | middle differentiated | 454 (66.2) | 381 (66.5) | 73 (64.6) | | | Poorly differentiated | 167 (24.3) | 133 (23.2) | 34 (30.1) | | | Undifferentiated | 2 (0.3) | 2 (0.3) | 0 (0) | | | Missing | 14 (2.0) | 13 (2.3) | 1 (0.9) | | Depth of tumor | T1a–1b | 64 (9.3) | 53 (9.2) | 11 (9.7) | 0.983 | | | T2 | 132 (19.2) | 110 (19.2) | 22 (19.5) | | | T3 | 490 (71.4) | 410 (71.6) | 80 (70.8) | | Lymph node metastasis | N0 | 298 (43.4) | 245 (42.8) | 53 (46.9) | 0.686 | | | N1 | 215 (31.3) | 185 (32.3) | 30 (26.5) | | | N2 | 119 (17.3) | 98 (17.1) | 21 (18.6) | | | N3 | 54 (7.9) | 45 (7.9) | 9 (8.0) | | Pathological stage | 1a–1b | 117 (17.1) | 94 (16.4) | 23 (20.4) | 0.565 | | | 2a–2b | 230 (33.5) | 195 (34.0) | 35 (31.0) | | | 3a–3c | 339 (49.4) | 284 (49.6) | 55 (48.7) | | Vessel invasive | Yes | 210 (30.6) | 173 (30.2) | 37 (32.7) | 0.591 | | | No | 476 (69.4) | 400 (69.8) | 76 (67.3) | | Nerve infiltration | Yes | 256 (37.3) | 208 (36.3) | 48 (42.5) | 0.215 | | | No | 430 (62.7) | 365 (63.7) | 65 (57.5) | | Treatment regimen | S | 464 (67.6) | 384 (67.0) | 80 (70.8) | 0.710 | | | S + postoperative C | 157 (22.9) | 133 (23.2) | 24 (21.2) | | | S + postoperative CRT | 65 (9.5) | 56 (9.8) | 9 (8.0) | | Hospital time (days) | ⩽14 | 542 (79.0) | 460 (80.3) | 82 (72.6) | 0.066 | | | 14 | 144 (21.0) | 113 (19.7) | 31 (27.4) | | Pre-AMC | Median | 0.5 (0.4-0.6) | 0.5 (0.4-0.6) | 0.7 (0.5-0.9) | <0.001 | | Post-AMC | Median | 0.7 (0.6-0.9) | 0.8 (0.6-1.0) | 0.5 (0.3-0.6) | <0.001 | | Pre-Platelet | Median | 201 (160-238) | 206.5 (149.5-244.0) | 200.0 (162.8-237.3) | 0.500 | | Post-Platelet | Median | 261 (200-331) | 263.0 (202.0-332.3) | 251.5 (177.0-324.0) | 0.074 |
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S, surgery; C, chemotherapy; CRT, chemoradiotherapy; Pre-AMC: preoperative absolute monocyte count; Post-AMC: postoperative absolute monocyte count; AMCc: postoperative absolute monocyte count change; Pre-platelet: preoperative platelet; Post-platelet: postoperative platelet.
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