Review Article

Medical Cannabinoids for Cancer Cachexia: A Systematic Review and Meta-Analysis

Table 1

Research summaries comparing the effects of cannabinoids and placebo.

Study IDStudy methodHuman subjectsInterventional groupControl groupFollow-up (d)Outcomes

Brisbois 2011parallel-group RCTsadvanced cancer patientsTHC (2.5 mg, n = 24)Placebo (n = 22)19Appetite, AEs, QOL
Johnson 2010parallel-group RCTsadvanced cancer patientsTHC:CBD extract (2.7 mg THC and 2.5 mg CBD, n = 60), THC extract (2.7 mg THC, n = 58)Placebo (n = 59)14Appetite, AEs, QOL
Strasser 2006parallel-group RCTsadvanced cancer patientsCE (standardized for 2.5 mg THC and 1 mg cannabidiol, n = 95) or THC (2.5 mg, n = 100)Placebo (n = 48)42Body Weight, Appetite, AEs, QOL