Local Biological Reactions and Pseudotumor-Like Tissue Formation in relation to Metal Wear in a Murine In Vivo Model

Figure 5

HE staining of sections of the murine knee joints. Histological sections of the MP group showing lymphocytic infiltrates () in tissue and fibrin exudation (black arrow). Aggregates of metallic wear particles (white arrow) were seen around the necrotic connective tissue (#); capillaries can be found in the obvious inflammatory tissues. Meanwhile, the original synovial membrane (like PBS group, yellow arrow) has been changed. There are some abnormalities of the bone structure between cortical bone and synovial tissue (gray arrow).