Research Article
Quantitative Proteomic Analysis Reveals the Deregulation of Nicotinamide Adenine Dinucleotide Metabolism and CD38 in Inflammatory Bowel Disease
Table 1
Novel proteins showing abundance changes in CD or UC patients.
| UniProt accession | Protein | UC/Con | CD/Con | CD/UC | Unique peptides | GI related or not | Fold change | p value | Fold change | p value | Fold change | p value |
| P36222 | CHI3L1 | 3.42 | 0.0434 | 3.13 | 0.0048 | 0.92 | 0.7712 | 4 | not | P28907 | CD38 | 2.28 | 0.0015 | 2.70 | 0.0004 | 1.18 | 0.2881 | 9 | not | Q6UX06 | OLFM4 | 2.32 | 0.0779 | 1.89 | 0.0030 | 0.81 | 0.4557 | 5 | not | Q8WWA0 | ITLN1 | 0.50 | 0.0048 | 0.36 | 0.0000 | 0.73 | 0.1718 | 6 | yes |
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CD, Crohn’s disease. UC, ulcerative colitis. Con, control. GI, gastrointestinal.
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