Citrus aurantium Ameliorates Cisplatin-Induced Nephrotoxicity

Table 1

Effect of crude extract of C. aurantium on body weight in rats treated with cisplatin.

Days of observation
Groups	0^th day	7^th day	14^th day	21^st day
Control	241 ± 7.5	261 ± 8.0	328 ± 8.7	310 ± 8.2
Cisplatin	245 ± 8.0	187 ± 9.2	198 ± 11	163 ± 8.4
Cisplatin + C. aurantium (200 mg/kg)	261 ± 8.0	220 ± 7.9	241 ± 8.3	229 ± 11
Cisplatin + C. aurantium (400 mg/kg)	263 ± 8.2	229 ± 5.6	282 ± 8.5	270 ± 9.3

Statistical analysis was done through one-way analysis of variance (ANOVA) trailed by Bonferroni post hoc test for all groups in respective days. The results are considered significant () if . , . Results were compared in a column with the respective control values.