Research Article

Citrus aurantium Ameliorates Cisplatin-Induced Nephrotoxicity

Table 7

Effect of crude extract of C. aurantium on absolute potassium excretion in rats treated with cisplatin

Days of observation
ParameterGroups0 day7th day14th day21st day

Absolute excretion of potassiumControl0.0062 ± 0.000700.0039 ± 0.000870.0029 ± 0.000270.0024 ± 0.00048
Cisplatin0.0055 ± 0.000890.0057 ± 0.000420.0061 ± 0.000370.0067 ± 0.00092
Cisplatin + C. aurantium (200 mg/kg)0.0055 ± 0.00960.0043 ± 0.000690.0041 ± 0.000630.042 ± 0.00055
Cisplatin + C. aurantium (400 mg/kg)0.0057 ± 0.00710.0023 ± 0.000450.0018 ± 0.000510.034 ± 0.00057

Statistical analysis was done through one-way analysis of variance (ANOVA) trailed by Bonferroni post hoc test for all groups in respective days. The results are considered significant () if . . Results were compared in a column with the respective control values.