Citrus aurantium Ameliorates Cisplatin-Induced Nephrotoxicity

Table 8

Effect of crude extract of C. aurantium on urinary sodium to potassium ratio in rats treated with cisplatin.

		Days of observation
Parameter	Groups	0^th day	7^th day	14^th day	21^st day
Urinary Na^2+/K^+ ratio	Control	4.7 ± 0.56	3.4 ± 0.48	3.3 ± 0.45	3.7 ± 0.44
	Cisplatin	5.1 ± 0.47	16 ± 1.3	19 ± 0.83	20 ± 3.7
	Cisplatin + C. aurantium (200 mg/kg)	6.0 ± 0.68	11 ± 1.4	8.3 ± 0.67	10 ± 1.2
	Cisplatin + C. aurantium (400 mg/kg)	4.7 ± 0.42	5.7 ± 0.61	4.6 ± 0.43	6 ± 0.81

Statistical analysis was done through one-way analysis of variance (ANOVA) trailed by Bonferroni post hoc test for all groups in respective days. The results are considered significant () if . , . Results were compared in a column with the respective control values.