Antiplasmodial Activity Assay of 3-Chloro-4-(4-chlorophenoxy) Aniline Combinations with Artesunate or Chloroquine In Vitro and in a Mouse Model

Table 1

In vivo individual drug assays.

Drug dosages	Animal test population groups
	I	II	III	IV
AS (mg/kg/day)	5	2.5	1.25	0.65
CQ (mg/kg/day)	5	2.5	1.25	0.65
ANI (mg/kg/day)	10	5	2.5	1.25
Control	—	—	—	—

The starting concentrations were chosen based on the existing literature except for the novel drug ANI that was on trial.