Research Article

Antiplasmodial Activity Assay of 3-Chloro-4-(4-chlorophenoxy) Aniline Combinations with Artesunate or Chloroquine In Vitro and in a Mouse Model

Table 4

IC50 and selective index values for drug combinations against Vero E6 and 3D7 cells.

DrugIC50μg/ml
Vero E63D7SI

AS-ANI35.432.613.6
CQ-ANI41.133.113.3

Selective index for safety analysis: selective indices were over 10 times the ED50 values of individual drugs thus safe.