Antiplasmodial Activity Assay of 3-Chloro-4-(4-chlorophenoxy) Aniline Combinations with Artesunate or Chloroquine In Vitro and in a Mouse Model

Table 5

Antiplasmodial activity of AS, CQ, and ANI on day 4 pi against P. berghei ANKA.

Drug	Inhibitory concentrations (mg/kg/day) on day 4 pi
	ED50	ED90
AS	2.22	4.2
CQ	2.38	4.75
ANI	4.18	9.1

The effective doses inhibit growth of parasites by 50% (ED₅₀). AS is two-fold more effective than ANI.