Potential Protective Effect of Achillea fragrantissima against Adriamycin-Induced Cardiotoxicity in Rats via an Antioxidant and Anti-Inflammatory Pathway

Table 4

Effects of A. fragrantissima on heart tissue concentration of TBARS, GSH-PX, and GSH measured in control and Adr-induced cardiotoxic rats.

Experimental Groups	TBARS	GSH-PX	GSH
	(nmol/g tissue)	(nmol/mg tissue)	(nmol/g tissue)
Control	4.76 ± 0.49	27.89 ± 1.51	4.34 ± 0.08
A. fragrantissima 800	4.51 ± 0.46	28.12 ± 1.87	4.75 ± 0.15
Adr	9.16 ± 0.84	12.73 ± 1.66	1.78 ± 0.06
A. fragrantissima 400 + Adr	6.29 ± 0.53	23.61 ± 1.58	3.61 ± 0.12
A. fragrantissima 800 + Adr	5.18 ± 0.44	27.17 ± 1.44	4.14 ± 0.09

Data are represented as mean ± SE (n = 10). Significant versus control group, significant versus Adr group, and significant between low and high dose group. p ≤ 0.05.