Tongxinluo Attenuates Myocardiac Fibrosis after Acute Myocardial Infarction in Rats via Inhibition of Endothelial-to-Mesenchymal Transition

Figure 1

Echocardiographic data show that TXL improves cardiac function of rat after AMI. (a) Cardiac function 4 weeks after AMI was examined by echocardiography. M-mode tracings of the left ventricles were recorded at the parasternal long-axis view. (b) The M-mode pictures were analyzed. LVEDD and LVESD were increased whereas EF and FS were decreased in model group. TXL improves cardiac function including reduced LVEDD, LVESD and preserved left ventricular EF and FS compared with model group. n=10, P<0.01 vs. control group; ^## P<0.01 vs. model group; P <0.05 P <0.01 vs. benazepril group.

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