Hepatoid Adenocarcinoma of Stomach: Emphasis on the Clinical Relationship with Alpha-Fetoprotein-Positive Gastric Cancer

Figure 1

Histologic features of hepatoid adenocarcinoma of stomach (HAS). (a) Hepatoid component (lower part of image) and normal gastric mucosa component (right part of image) are visible. (b) Tumor cells with abundant eosinophilic granular hepatocyte-like neoplastic cells and nucleus were large and ovoid and contained 1-2 nucleoli. (c) Normal gastric mucosa morphology. (d) Typical hepatoid area of HAS proliferation in solid nest fashion. (e) Typical hepatoid area of HAS proliferation in trabecular pattern. (f) Focally, the HAS tumor cells form glandular structures. (g) The lymph node that has not been invaded by the tumor.