Comparison of Intravenous Dexmedetomidine versus Esmolol for Attenuation of Hemodynamic Response to Tracheal Intubation after Rapid Sequence Induction: A Systematic Review and Meta-Analysis

Table 1

Baseline characteristics of included studies.

Study name	Year	ASA classification	Age (yr)	Intervention	Comparison	Drug for induction of anesthesia
Subhadeep Chakraborty	2018	I and II	30-60	dexmedetomidine 1 μg/kg	esmolol 2 mg/kg	ondansetron 0.08 mg/kg, glycopyrrolate 0.004 mg/kg, midazolam 0.02 mg/kg, thiopentone sodium 5 mg/kg and intubated after succinylcholine 2 mg/kg
Sandeep Sharma	2018	I and II	20-50	dexmedetomidine 1 μg/kg	esmolol 1.5 mg/kg	midazolam 0.03 mg/kg, fentanyl 1 μg/kg, propofol 2.5 mg/kg and succinylcholine 2 mg/kg
Venkatesh Selvaraj	2016	I	18–60	dexmedetomidine 1 μg/kg	esmolol 0.5 mg/kg	NR
Hema B	2016	I and II	18–60	dexmedetomidine 1 μg/kg	esmolol 1 mg/kg	glycopyrrolate 0.004 mg/kg, fentanyl 1μg/kg, thiopentone 5 mg/kg and vecuronium 0.1mg/kg
Bajwa S. J.	2016	I and II	18–55	dexmedetomidine 1 μg/kg	esmolol 1 mg/kg	thiopentone 5 mg/kg, fentanyl 1μg/kg and vecuronium 0.1mg/kg
Bhattacharjee D. P.	2016	I and II	20-60	dexmedetomidine 1 μg/kg	esmolol 0.5 mg/kg	fentanyl 2 μg/kg, propofol 2 mg/kg and rocuronium 0.7 mg/kg
Prashant Dass	2015	I and II	18–65	dexmedetomidine 0.5 μg/kg	esmolol 0.3 mg/kg	thiopental sodium 2 μg/kg, fentanyl 2 μg/kg and vecuronium bromide 0.1 mg/kg
Velayudha Reddy	2014	I and II	40-60	dexmedetomidine 1 μg/kg	esmolol 2 mg/kg	ondansetron 0.08 mg/kg, glycopyrrolate 0.004 mg/kg, thiopentone 5.0 mg/kg and succinylcholine 2.0 mg/kg
Erbesler Z. A.	2013	I and II	18–65	dexmedetomidine 0.5 μg/kg	esmolol 0.5 mg/kg	0.03 mg midazolam, propofol 2 mg/kg, remifentanil 1 μg/kg and rocuronium 0.6 mg/kg
B. Yavascaoglu	2008	I and II	18-60	dexmedetomidine 0.5 μg/kg	esmolol 0.3 mg/kg	midazolam 0.03mg kg, fentanyl 2 μg/kg, rocuronium 0.6 mg/kg and propofol NR

ASA: American Society of Anesthesiologists-Physical Status; yr: years; NR: not recorded.