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BioMed Research International
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2019
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Article
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Tab 1
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Research Article
A High Throughput HPLC-MS/MS Method for Antihypertensive Drugs Determination in Plasma and Its Application on Pharmacokinetic Interaction Study with Shuxuetong Injection in Rats
Table 1
Mass spectra properties of the analytes and IS.
Compounds
Precursor Ion (m/z)
Product Ion (m/z)
Frag. (V)
C.E. (V)
metoprolol tartrate
268.1
121.0
95
20
hydrochlorothiazide
295.8
205.2
115
-16
nifedipine
347.1
254.1
91
14
valsartan
434.2
179.0
123
-20
methyclothiazide(IS)
357.9
321.8
135
-3