Preoperative Mean Platelet Volume and Platelet Distribution Width Predict Postoperative Sepsis in Patients with Colorectal Cancer
Table 1
Baseline characteristics of CRC patients stratified by development of sepsis status after operation.
Variables
Sepsis,
Nonsepsis,
value
Age (years)
63.4 ± 9.7
63.4 ± 9.0
0.993
Gender (male, %)
33 (60.0)
99 (60.0)
1.000
BMI (kg/m2)
23.5 ± 3.1
23.5 ± 3.3
0.927
Smoker (%)
9 (16.4)
33 (20.0)
0.552
Drinking (%)
8 (14.5)
35 (21.2)
0.280
WBC (×109/L)
8.58 ± 6.08
7.15 ± 2.63
0.093
Hemoglobin (g/L)
113.4 ± 26.7
130.6 ± 24.6
<0.001
Platelet count (×109/L)
272.5 ± 131.8
272.5 ± 84.4
0.999
MPV (fL)
9.6 ± 1.3
8.4 ± 1.7
<0.001
PDW (%)
14.6 ± 2.8
17.2 ± 1.1
<0.001
Creatinine (umol/L)
84.1 ± 37.4
88.0 ± 20.9
0.460
Albumin (g/L)
35.0 ± 6.9
44.7 ± 6.8
<0.001
LDH (U/L)
166 (146–193)
145 (125.5–179)
0.003
ALP (U/L)
83.0 (68.0–108.0)
87.0 (75.0–109.0)
0.196
Fibrinogen (g/L)
3.44 ± 1.02
3.69 ± 1.03
0.126
CEA (ng/ml)
5.16 (2.19–11.64)
4.72 (2.26–15.78)
0.779
Comorbidities, n (%)
Coronary artery disease
10 (18.2)
33 (20.0)
0.768
COPD
0
0
Hypertension
12 (21.8)
27 (16.4)
0.359
Diabetes mellitus
10 (18.2)
31 (18.8)
0.920
APACHE II score
17 (12–22)
13 (11–14)
<0.001
SOFA score
9 (6–10)
6 (6–8)
0.005
Length of ICU stay, median (IQR)
4 (1–7)
1 (1–1)
<0.001
ICU mortality (%)
15 (27.3)
0 (0)
<0.001
Tumor location
0.392
Colon
31 (56.4)
82 (49.7)
Rectum
24 (43.6)
83 (50.3)
Tumor size (cm)
0.576
<5.0
32 (58.2)
103 (62.4)
≥5.0
23 (41.8)
62 (37.6)
Histology differentiation
0.322
Well/moderately
47 (85.5)
131 (79.4)
Poorly
8 (14.5)
34 (20.6)
Data are expressed as mean (SD) or percentage. SD, standard deviation; BMI, body mass index; WBC, white blood cell; BUN, blood urea nitrogen; CEA, carcinoembryonic antigen; FPG, fasting plasma glucose; LDH, lactate dehydrogenase; ALP, alkaline phosphatase; ICU, intensive care unit; SOFA, Sequential Organ Failure Assessment; APACHE, Acute Physiology and Chronic Health Evaluation; IQR, 25% and 75% interquartile range; COPD, chronic obstructive pulmonary disease.
