Research Article
14-CpG-Based Signature Improves the Prognosis Prediction of Hepatocellular Carcinoma Patients
Table 6
Stratified survival analysis of the MSH based on major clinicopathological factors in the total cohort.
| Variable | High risk | Low risk | HR (95% CI) | value |
| Cirrhosis | | | | | Yes | 32 | 47 | 3.089 (1.526–9.387) | 0.007 | No | 70 | 66 | 4.97 (2.576–8.31) | 0.000 | Child-Pugh stage | | | | | A | 102 | 120 | 3.915 (2.383–6.645) | 0.000 | B | 12 | 10 | 2.735 (0.669–9.308) | 0.182 | Tumor histologic grade | | | | | G1/G2 | 118 | 115 | 2.834 (1.779–4.283) | 0.000 | G3/G4 | 65 | 67 | 4.002 (2.33–7.386) | 0.000 | AJCC TNM stage | | | | | Stage I/II | 119 | 140 | 3.671 (2.473–6.516) | 0.000 | Stage III/IV | 54 | 34 | 2.138 (1.123–3.584) | 0.021 | AFP | | | | | ≤25 | 74 | 92 | 4.425 (2.601–9.364) | 0.000 | >25 | 60 | 56 | 2.228 (1.226–3.95) | 0.009 | Surgical margin status | | | | | R0 | 157 | 169 | 3.402 (2.361–5.011) | 0.000 | R1 | 11 | 7 | 1.775 (0.411–7.656) | 0.4419 |
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