14-CpG-Based Signature Improves the Prognosis Prediction of Hepatocellular Carcinoma Patients

Table 6

Stratified survival analysis of the MSH based on major clinicopathological factors in the total cohort.

Variable	High risk	Low risk	HR (95% CI)	value
Cirrhosis
Yes	32	47	3.089 (1.526–9.387)	0.007
No	70	66	4.97 (2.576–8.31)	0.000
Child-Pugh stage
A	102	120	3.915 (2.383–6.645)	0.000
B	12	10	2.735 (0.669–9.308)	0.182
Tumor histologic grade
G1/G2	118	115	2.834 (1.779–4.283)	0.000
G3/G4	65	67	4.002 (2.33–7.386)	0.000
AJCC TNM stage
Stage I/II	119	140	3.671 (2.473–6.516)	0.000
Stage III/IV	54	34	2.138 (1.123–3.584)	0.021
AFP
≤25	74	92	4.425 (2.601–9.364)	0.000
>25	60	56	2.228 (1.226–3.95)	0.009
Surgical margin status
R0	157	169	3.402 (2.361–5.011)	0.000
R1	11	7	1.775 (0.411–7.656)	0.4419