Review Article

A Meta-Analysis of 13 Randomized Trials on Traditional Chinese Medicine as Adjunctive Therapy for COVID-19: Novel Insights into Lianhua Qingwen

Table 3

The outcomes of this meta-analysis.

OutcomesStudies NumbersSample sizeOverall effectHeterogeneity
ExperimentControlEffect estimates95% CIs value (%) value

Traditional Chinese medicine as the adjunctive therapy for COVID-19
Total effective8484/569347/5491.259-1.46474.8%
Improvement of chest CT6333/431268/4331.143-1.3560.0%
Fever improvement3127/14178/99-0.063-0.28384.1%
Cough improvement399/13760/1031.057-1.5700.0%
Conversion to severe cases530 of 48072 of 4600.275-0.6059%
The subgroup of Lianhua Qingwen as the adjunctive therapy for COVID-19
Total effective3264/324216/3311.136-1.3710.0%
Improvement of chest CT3252/324210/3311.110-1.35634.3%
Conversion to severe cases429/41063/4170.311-0.7070.0%

Note: CIs = confidence intervals; RD = rate difference; OR = odds ratio.