Research Article

Computational Modeling and Evaluation of Potential mRNA and Peptide-Based Vaccine against Marburg Virus (MARV) to Provide Immune Protection against Hemorrhagic Fever

Table 2

CTL epitopes presented with respective binding affinity and physiochemical characteristics.

ProteinIDPeptideCombAntigenicityImmunogenicitySolubilityToxicity

Envelope glycoprotein577TTEERTFSL0.871.040.221.814-1.35
652LTNLGILLL0.911.270.120.219-1.12

VP30101LTNRELLLL0.781.130.121.395-1.07

VP24136ISPNLLGIY1.491.050.070.958-1.36

Antigenicity greater than 0.4, immunogenic less than 1, solubility greater than 1, and toxicity score lower than 0.