Research Article

Computational Modeling and Evaluation of Potential mRNA and Peptide-Based Vaccine against Marburg Virus (MARV) to Provide Immune Protection against Hemorrhagic Fever

Table 5

Selected T cell epitopes with their corresponding HLA molecules.

CTL epitopes
ProteinIDPeptideHLAPDB ID
Envelope glycoprotein577TTEERTFSLHLA-B08:017NUI
652LTNLGILLLHLA-B58:015VWH
VP30101LTNRELLLLHLA-B58:015VWH
VP24136ISPNLLGIYHLA-A01:014NQX

HTL epitopes
ProteinsStart-endPeptideHLAPDB ID
Envelope glycoprotein425-439AQHLVYFRRKRSILWHLA-DRB115:011BX2
VP30178-192NRELLLLMARKMLPNHLA-DRB115:011BX2
123-137TLENLGHILSYLHRSHLA-DRB115:011BX2
VP24150-164SEWLLLEVTSAIHISHLA-DRB107:016BIJ