Hematological and Biochemical Laboratory Parameters in COVID-19 Patients: A Retrospective Modeling Study of Severity and Mortality Predictors
Table 2
Hematological data of all patients: deceased, recovered, severe, and nonsevere COVID-19 cases.
Variables
Normal range
Total
Outcome
value
Severity
value
Deceased
Recovered
Severe
Nonsevere
WBC (×109/L)
4.2-10.8
11.7 (8.4-15.8)
11.7 (8.4-15.8)
7.6 (5.3-10.3)
<0.001
11.5 (8.1-15.4)
7.7 (5.3-10.4)
<0.001
LYM (×109/L)
1.5-4.5
0.8 (0.5-1.1)
0.8 (0.5-1.1)
1 (0.6-1.5)
0.007
0.8 (0.5-1.1)
1 (0.7-1.5)
0.002
NEU (×109/L)
1.7-7.9
6 (4-9)
10 (7-14)
6 (4-8)
<0.001
10 (6-14)
8 (6-12)
<0.001
NLR
7 (3.5-11.12)
12.14 (7.5-17.6)
5.6 (3.2-9.8)
<0.001
12.43 (7.3-17.6)
5.6 (3.2-9.8)
<0.001
MO (×109/L)
0.1-0.9
0.1 (0.04-0.17)
0.04 (0-0.13)
0.09 (0-0.16)
0.13
0.06 (0-0.19)
0.1 (0.05-0.16)
0.009
EOS (×109/L)
0.02-0.55
0.09 (0-0.16)
0.04 (0-0.13)
0.09 (0-0.16)
0.03
0.04 (0-0.13)
0.09 (0-0.16)
0.007
RBC (×1012/L)
4.2-5.65
4.4 (3.95-4.85)
4.14 (3.5-4.6)
4.4 (4-4.8)
<0.001
4.1 (3.5-4.7)
4.4 (4-4.8)
0.001
HGB (g/dl)
12-15
<0.001
0.001
PLT (×109/L)
160-385
220 (169-288)
213 (147.5-245)
224 (174-297)
0.002
215 (144.2-251)
223 (174.7-297.2)
0.004
HCT (%)
38-49
0.001
0.013
MCV (fl)
80-98
87.2 (83.8-90.6)
87 (84.9-90.86)
87 (83.69-90.63)
0.259
87.5 (84.8-90.67)
87.1 (83.1-90.7)
0.385
MCH (pg)
28-32
29.14 (27.5-30.4)
28.9 (27.5-30)
29.2 (27.4-30.5)
0.395
28.9 (27.5-30.1)
29.2 (27.5-30.5)
0.504
MCHC (g/dl)
33-36
0.003
0.001
ESR (mm/hr)
0-20
46 (27-66)
54 (34-81)
44 (26-64)
0.025
50.5 (30-81.5)
45 (26.75-65)
0.249
INR
0.8-1.2
1.1 (1-1.2)
1.2 (1.1-1.45)
1.08 (1-1.17)
<0.001
1.23 (1.1-1.48)
1.08 (1-1.15)
<0.001
PT (sec)
11-13
13.2 (12.5-14.1)
13.95 (13.1-16)
13 (12.5-13.8)
<0.001
14.2 (13.1-16.17)
13 (12.5-13.8)
<0.001
PTT (sec)
21-32
32 (28.1-36.1)
33 (28.9-37.7)
31.7 (28-35.1)
0.063
32.6 (28.8-37)
31.8 (28-35.2)
0.282
Note: Data are and median (IQR). values for differences between the two groups were obtained by the Student -test or the Mann–Whitney U test. IQR: interquartile range; WBC: white blood cells; LYM: lymphocytes; NEU: neutrophil; NLR: neutrophil-to-lymphocyte ratio; MO: monocyte; monocyte-to-lymphocyte ratio; EOS: eosinophil; RBC: red blood cells; HGB: hemoglobin; PLT: platelet cells; HCT: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; ESR: erythrocyte sedimentation rate; INR: international normalized ratio; PT: prothrombin time; PTT: partial thromboplastin time. The threshold for significance is the Bonferroni-corrected from to .
