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Mucosal Immunity to Infectious Diseases

Call for Papers

Mucosal surfaces, such as the gastrointestinal tract, respiratory tract, urogenital tracts, and ocular surface, are a key portal of entry for the majority of medically relevant infectious diseases. Additionally, mucosal surfaces pose a number of difficult tasks for the immune system, which include an enormous surface area that must be patrolled for infection or barrier breach, regulating immune responses to extremely high levels of inert antigens and nonpathogenic or commensal microorganisms. The intestinal mucosa is constantly exposed to a wide range of commensal and potentially pathogenic microbial species. This chronic exposure to inflammatory mediators and nonpathogenic organisms requires that the generation of an appropriate immune response against bona fide pathogens be tightly regulated to prevent overt inflammation. Recently there has been an explosive growth in our understanding of how the mucosal immune system achieves these tasks. We invite authors to submit original research and review articles that seek to define the interaction of innate and adaptive immune cells with bacterial, viral, fungal, protozoan, and helminth infections at mucosal surfaces. We are interested in articles that explore all aspects of antimicrobial immunity at mucosal surfaces. Potential topics include, but are not limited to:

  • Role of nonhematopoietic cells in regulating antimicrobial immunity
  • Role of tissue sentinel innate immune cells in initiating and regulating the antimicrobial response
  • Balance of pathogen clearance with tissue pathology at mucosal surfaces
  • Role of tissue resident memory cells in antimicrobial immunity
  • Importance of mucosal vaccination strategies to limit microbial infection at mucosal surfaces
  • Identifying mechanisms for modulating mucosal immunity to either enhance or dampen inflammation as necessary
  • Regulation of the immune system development and function by the microbiome
  • Understanding the homing and maintenance of mucosal immune cell populations
  • Role of mucosal-associated lymphoid tissues in immunity

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/immunology/miid/ according to the following timetable:

Manuscript DueFriday, 27 June 2014
First Round of ReviewsFriday, 19 September 2014
Publication DateFriday, 14 November 2014

Lead Guest Editor

  • Joshua J. Obar, Department of Immunology & Infectious Diseases, Montana State University, Bozeman, MT, USA

Guest Editors

  • Brian S. Sheridan, Department of Immunology, University of Connecticut Health Center, Farmington, CT, USA
  • Jerod A. Skyberg, Department of Veterinary Pathobiology, University of Missouri, Columbia, MO, USA