Biomarkers of Metabolic Disorders: Diagnostic and Prognostic Values and Insights into the Pathogenesis
1Translational Medical Center, Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated to Sixth People’s Hospital, Shanghai 200233, China
2Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
3University of Hawaii Cancer Center, Honolulu, HI, USA
Biomarkers of Metabolic Disorders: Diagnostic and Prognostic Values and Insights into the Pathogenesis
Description
In recent decades, overwhelming evidence has indicated that metabolic disorders, including obesity, diabetes, dyslipidemia, and nonalcohol fatty liver disease, are the leading cause of disability and death. However, the pathogenesis of metabolic disorder and its chronic complications involve multiple biological pathways and are largely unknown. Biological markers, or biomarkers, are alterations and biological characteristics that can be evaluated as indicators of pathogenic processes or pharmacological responses to therapeutic interventions. In consequence, it is imperative for researchers to search for the biomarkers of the metabolic disorders using systemic biology approaches and evaluate their effects in different ethnic populations, which may provide potential diagnostic markers as well as drug targets for the disease and shed more light on the mechanisms.
This special issue mainly focuses on the current advancement in the field of biomarkers of metabolic disorders. We cordially invite scientists and investigators to contribute both your original research manuscripts and review articles that will stimulate the further research activities in this rising field and enhance our existing knowledge of biomarkers in metabolic disorders. Potential topics include, but are not limited to:
- Studies searching for genetic and genomic markers for metabolic disorders
- Proteomic and metabolomic studies searching for biomarkers for metabolic disorders
- Studies evaluating the diagnostic and prognostic effects of biomarkers and metabolic disorders in different ethnic populations
- Mechanism studies derived from known biomarkers to explicit the pathogenesis of diseases
- Latest technologies for promoting the new discoveries of biomarkers
- Reviews addressing issues related to the accomplishment of biomarkers and their applications
Before submission, authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/biochemistry/bmd/ according to the following timetable: