Helicobacter pylori and Pathogenesis
1Tokyo Medical University, Tokyo, Japan
2Kyorin University School of Medicine, Tokyo, Japan
3Keio University School of Medicine, Tokyo, Japan
Helicobacter pylori and Pathogenesis
Description
Helicobacter pylori is a causative agent for chronic gastritis, peptic ulcer diseases, gastric cancer, and MALT lymphoma. In addition, an association of extragastric diseases including idiopathic thrombocytopenic purpura, iron deficiency anemia, atopic dermatitis, and so on with H. pylori is reported. Eradication therapy using a combination regimen with proton pump inhibitor and antimicrobial agents for H. pylori infection has been established, and it is now possible by the therapy to prevent malignant diseases including gastric cancer. However, the details on the mechanism(s) by which H. pylori infection induces pathogenesis in humans remain to be determined.
We invite authors to submit original research and review articles that seek to clarify pathogenic role of H. pylori. We are interested in articles that explore aspects of pathogenesis caused by H. pylori infection. In addition, translational researches from basic studies to development of innovative diagnostic procedures and clinical treatments are expected to be submitted.
Potential topics include, but are not limited to:
- Microbiology of H. pylori
- Strain diversity of H. pylori strains
- Omics of H. pylori infection
- Animal model of H. pylori infection
- Virulence factors of H. pylori
- Mucosal immunity and of H. pylori infection
- Carcinogenesis by H. pylori infection
- Translational studies for diagnosis and clinical treatment of H. pylori infection