During the last decade, new bearing materials, new methods in in vitro wear simulation, specific cell culture and animal models to evaluate the response to particulate debris, and dedicated retrieval analysis programs to learn more about material degradation in vivo have been developed in the field of biotribology.

Improvements in knee arthroplasty design, materials, sterilisation techniques, oxidation resistance, and articulating surface treatments have led to superior performance of total knee prostheses by reducing the prevalence of disastrous wear, delamination, and structural fatigue and are expected to show substantial benefits in decreasing wear and osteolysis in the future.

As total knee arthroplasty today is being increasingly performed on younger, heavier, and more active patients, it appears desirable to reduce wear and further improve bearing materials and implant designs in the next decade.

For this special issue on Biotribology in Knee Arthroplasty, researchers are invited to contribute original research papers as well as review articles that will stimulate discussion and the continuing efforts to understand all dimensions of biotribology in knee arthroplasty. Potential topics include, but are not limited to:

• Articulations in artificial knee joint replacements
• Artificial materials in articulation with cartilage
• New bearing materials/material modifications
• In vitro wear simulation/new test methods
• Impingement or subluxation conditions
• Computational models in knee wear simulation
• In vivo models
• Clinical findings
• Retrieval analysis
• Biological response to particulate debris
• Implant allergy–metal ion hypersensitivity

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/biomaterials/btrib/ according to the following timetable: