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Tick-borne Encephalitis: Ecology of TBE Virus, Epidemiology, Clinical Characteristics, Pathogenesis, Diagnostics, Treatment, and Prevention

Call for Papers

Tick-borne encephalitis (TBE) is a zoonosis endemic in a vast area of Europe and Asia. It is caused by TBE virus (TBEV). The genetic analysis of strains isolated in different geographic regions shows the existence of three subtypes of TBEV, designated as European, Siberian, and Far-Eastern subtype. Although TBE is a disease that is preventable by vaccination, thousands of people fall ill with tick-borne encephalitis annually. Clinical spectrum of the disease ranges from mild meningitis to severe meningoencephalitis with or without paralysis. Rare clinical manifestations are an abortive form of the disease and a chronic progressive form. A postencephalitic syndrome, causing long-lasting morbidity that often affects the quality of life and sometimes also forces the individual to a change in life-style, develops in 35–58% of patients after acute tick-borne encephalitis. Pathogenesis of the disease is rather vague and the knowledge on factors influencing the course and outcome of TBE, including incomplete recovery, is limited.

We invite investigators to contribute original research articles as well as review articles that will stimulate the understanding of the ecology and epidemiology of this zoonosis, and will elucidate clinical features, diagnostics, treatment, and prevention of TBE.

We are particularly interested in the articles describing the pathogenesis of the disease and the development of TBE in spite of vaccination, as well as reports on the factors affecting the severity of TBE and on the factors influencing the outcome of the infection with TBEV. Potential topics include, but are not limited to:

  • Recent developments in ecology of TBEV
  • Advances in TBEV research
  • Epidemiology of TBE
  • Reports on the development of TBE in spite of vaccination against TBE
  • Novelties in the pathogenesis of TBE
  • Recent advances and challenges in diagnostics, treatment, and prevention of TBE

Before submission authors should carefully read over the journal’s Author Guidelines, which can be found at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/virology/tbev/ according to the following timetable:

Manuscript DueFriday, 7 February 2014
First Round of ReviewsFriday, 2 May 2014
Publication DateFriday, 27 June 2014

Lead Guest Editor

  • Franc Strle, Department of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia

Guest Editors

  • Gerold Stanek, Medical University of Vienna, Istitute for Hygiene and Applied Immunology, Kinderspitalgasse, Vienna, Austria
  • Aukse Mickiene, Kaunas University of Medicine, Clinic of Infectious Diseases, Baltijos, Kaunas, Lithuania