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Genomic Sequence Variation and Posttranscriptional Modification on Gene Regulation and Function

Call for Papers

Genomic sequence variation and posttranscriptional modification of RNA transcripts lead to changes in gene regulation, regulation of gene networks, and protein function, which can then lead to pathogenesis and diseases. The past two decades have seen an explosion in research on these topics thanks to the rapid advance in high-throughput technologies.

This special issue invites authors to submit their research and review papers addressing important questions on how RNA editing and splicing and single nucleotide and multinucleotide variants (SNVs and MNVs, respectively) impact transcriptional and posttranscriptional regulation, translation, and protein function that collectively result in pathogenesis and diseases.

Potential topics include, but are not limited to:

  • MicroRNA regulation and gene expression
  • RNA editing and disease
  • Alternative splicing and gene regulation
  • RNA editing and disruption of miRNA function
  • Promoted RNA-induced gene silencing by SNVs/MNVs
  • Identification of RNA editing sites in miRNAs by deep sequencing
  • Application tools, databases, and novel approaches for miRNA, RNA editing, and SNV/MNV discovery and functional analysis
Manuscript DueFriday, 3 October 2014
First Round of ReviewsFriday, 26 December 2014
Publication DateFriday, 20 February 2015

Lead Guest Editor

  • Zihua Hu, State University of New York, Buffalo, USA

Guest Editors

  • Ping Liang, Brock University, St. Catharines, Canada
  • Song Liu, Roswell Park Cancer Institute, Buffalo, USA