Bone and tooth regeneration is an important issue especially for maxillofacial reconstructions. Autogenous graft has been the gold standard for hard tissue reconstruction due to its excellent clinical outcome. However, the disadvantages of using autogenous graft include the need to surgically invade secondary healthy donor sites, the amount of tissues that can be harvested, and the possibility of increasing the chances for tissue morbidity and infection. With the advent in biomaterials research, various implants materials have shown promise to be used as graft materials in the clinics. In this special issue, the current and latest clinical and basic science research on these materials will be reported.

Potential topics include, but are not limited to:

• Research on bone regeneration (biomaterial, cytokine, cell, etc.)
• Research on tooth regeneration (biomaterial, cytokine, cell, etc.)