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New insight into Cardiac CT Imaging of Atherosclerotic Cardiovascular Disease for Improvement of Risk Assessment

Call for Papers

Rapid developments in the CT technique, in particular, the increasingly worldwide use of coronary CT angiography, have demonstrated that coronary CT angiography has the potential to revolutionise how patients are risk-stratified by identifying rupture-prone, noncalcified, or mixed coronary plaques accurately and reliably. As our understanding of plaque histology has improved, there has been an increasing interest in the ability of coronary CT angiography to identify particularly the high-risk or vulnerable plaques. CT not only allows accurate detection of coronary atherosclerotic plaques but also enables quantitative analysis of plaque vessel area, lumen area, and plaque burden.

Attempts at plaque quantification and characterisation using coronary CT angiography have been successful, although further refinements regarding reproducibility, accuracy, and ability to predict future cardiac events are required. With further improvements in CT imaging processing and diagnostic value, coronary CT angiography will become part of the routine diagnostic approach for the detection of ‘vulnerable patient’ so that appropriate preventive strategies can be implemented in a targeted population.

We invite investigators to contribute original research articles as well as review articles that seek to better characterize coronary plaques, assess coronary lumen stenosis, and evaluate cardiac functional abnormality with the aim of improving cardiovascular disease risk assessment, thus, developing strategies to improve patient management.

We are particularly interested in articles describing the cardiac CT assessment of atherosclerotic plaques in patients with suspected coronary artery disease.

Potential topics include, but are not limited to:

  • Coronary CT angiography in the characterization of atherosclerotic plaque composition
  • Automatic or semiautomatic quantification of coronary artery plaque using coronary CT angiography
  • Correlation of coronary calcium score or calcium density with cardiovascular events
  • Prognostic value of coronary CT angiography in coronary artery disease
  • CT-derived FFR for assessment of hemodynamically significant coronary disease
  • New insight into functional assessment of coronary artery disease by cardiac CT
  • Correlation of coronary CT assessment of atherosclerotic plaques with myocardial perfusion imaging by SPECT or PET
  • Use of coronary CT to guide intervention
  • Coronary flow models by CT
Manuscript DueFriday, 3 October 2014
First Round of ReviewsFriday, 26 December 2014
Publication DateFriday, 20 February 2015

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