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Biophysical and Biochemical Aspects of Cytochrome C: From Electron Transfer to Biogenesis to Signaling Processes

Call for Papers

Cytochromes c (Cytcs) represent a large family of globular proteins with a characteristic α-helical fold whichcan bind one or several c-type hemes through two thioether bonds involving the sulfhydryl groups of cysteine(s) residue(s). Although they are classically considered textbook proteins, Cytcs are still providing novel clues about different aspects of protein biochemistry and biophysics, which are generally, but not always, dictated by the presence of the heme group(s).

We are interested in manuscripts that report the relevance of Cytcs in physiological processes as well as in manuscripts describing the utilization of c-type cytochromes in biophysical studies or biotechnological applications. Manuscript considered for publication in this special issue should be devoted to the problem of heme c attachment and Cytc biogenesis (including the characterization of the accessory proteins involved in this process in prokaryotes or eukaryotes), to the characterization of novel electron transfer reactions, to the study of Cytc stability and mechanism of folding, to the characterization of protein-protein interactions (e.g., complex formation with redox and nonredox partners), and lipid recognition. Potential topics include, but are not limited to:

  • Cytc biogenesis
  • Cytc folding mechanism and stability
  • Cytc in intermolecular recognition
  • Cytc electron transfer reactions
  • Cytc as biosensors

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/biochemistry/cyt/ according to the following timetable:

Manuscript DueFriday, 25 April 2014
First Round of ReviewsFriday, 18 July 2014
Publication DateFriday, 12 September 2014

Lead Guest Editor

Guest Editors

  • Adele Di Matteo, Institute of Biology and Molecular Pathology, CNR, Rome, Italy
  • Francesco Malatesta, Department of Biochemical Sciences, Sapienza, University of Rome, Rome, Italy
  • Tewfik Soulimane, Chemical & Environmental Sciences Department, University of Limerick, Limerick, Ireland