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CT Cardiac Imaging: From Atherosclerosis to Acute Coronary Syndromes

Call for Papers

Coronary artery disease (CAD) is the leading cause of death worldwide. For several years now researches have been focusing on the possibility of visualizing CAD in both its subclinical and clinical phases for improving risk stratification and management. In this setting, noninvasive imaging by coronary computed tomography angiography (CCTA) has emerged as accurate diagnostic alternative to conventional coronary angiography, which is still today the standard criterion for the evaluation of CAD. However, anatomic assessment of CAD is not well correlated with the functional significance of myocardial ischemia on noninvasive functional test (e.g., myocardial perfusion scintigraphy) or fractional flow reserve (FFR) measurement. Recent advances in CT technology have increased the ability to evaluate myocardial ischemia by dual-energy technique or dynamic myocardial volume perfusion imaging, offering functional information. Several studies suggested that CT assessment of myocardial perfusion is feasible and improves the diagnostic accuracy of CCTA in the detection of hemodynamically significant CAD. Furthermore, recent advances in computational fluid dynamics allow a noninvasive FFR derived from CT (FFR-CT) for diagnosis of CAD.

We invite authors to submit original research and review articles that explore the role of CT cardiac imaging in the evaluation of CAD. We are interested in articles that explore aspects of the anatomic and the functional significance of CAD.

Potential topics include, but are not limited to:

  • Evaluation of CAD burden by CCTA in general and selected populations
  • Role of CCTA in risk stratification and management
  • Coronary plaque analysis with CCTA in both the acute and stable settings
  • Evaluation of patients with acute chest pain and possible acute coronary syndrome
  • Comparative/correlative studies between CCTA and other anatomic/functional imaging modalities
  • Role of dual-energy technique or dynamic volume CT perfusion imaging in detecting myocardial ischemia and viability
  • Emerging role and diagnostic accuracy of FFR-CT for diagnosis of CAD
  • Outcome analysis of atherosclerosis progression/regression after medical treatment
  • Prognostic value of CCTA to predict future ischemic event
Manuscript DueFriday, 13 February 2015
First Round of ReviewsFriday, 8 May 2015
Publication DateFriday, 3 July 2015

Lead Guest Editor

  • Sara Seitun, IST National Institute for Cancer Research, Genova, Italy

Guest Editors